Description

n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Propionamide is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures via cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, enabling the introduction of the pyridine-boronate moiety into target molecules.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology & Proteomics: Employed in the synthesis of chemical probes and affinity tags for studying protein function and interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific boronate functionalization.

Basic Information

Product Name	n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Propionamide
CAS No.	1285530-34-8
Molecular Formula	C14H21BN2O3
Molecular Weight	276.14 g/mol
Synonyms	2-Propionamido-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; N-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]propionamide; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-propionamidopyridine; Propionamide, N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]-; CAS 1285530-34-8
EINECS	Contact for details

Quality Control

Every batch of n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Propionamide is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation, meeting the stringent requirements for advanced synthetic intermediates. Certificates of Analysis (COA) with full analytical data are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.