Description

2-Methoxy-n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Acetamide is a high-value pharmaceutical intermediate and chemical building block, specifically a pyridine-containing boronic ester derivative. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern organic synthesis for creating complex carbon-carbon bonds. It is primarily needed by pharmaceutical R&D and fine chemical synthesis teams for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those containing biaryl or heterobiaryl motifs.
• Suzuki-Miyaura Cross-Coupling Reagent: Serves as a versatile boronic ester coupling partner for the introduction of the substituted pyridylacetamide moiety into target molecules.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Potential monomer or precursor for creating functional polymers, ligands for catalysts, or organic electronic materials.
• Chemical Biology & Proteomics: Can be utilized in the synthesis of molecular probes and tools for studying biological systems.
• Contract Research & Manufacturing (CRO/CMO): Essential raw material for custom synthesis and process development services.

Basic Information

Product Name	2-Methoxy-n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Acetamide
CAS No.	1285530-33-7
Molecular Formula	C16H25BN2O4
Molecular Weight	320.20 g/mol
Synonyms	2-Methoxy-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]acetamide; N-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)-2-methoxyacetamide; 2-Methoxyacetamide, N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]-; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-[(2-methoxyacetyl)amino]pyridine; 1285530-33-7; Pinacol ester of [2-[(2-methoxyacetyl)amino]pyridin-4-yl]boronic acid
EINECS	Contact for details

Quality Control

Our 2-Methoxy-n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from oxidation and hydrolysis. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.