Description

2-(2,4-Difluorophenyl)-1-(Pyridin-3-Yl)Ethan-1-One is a high-purity fluorinated aromatic ketone building block, essential for advanced organic synthesis. This compound is valued for its unique molecular scaffold, which incorporates both difluorophenyl and pyridinyl moieties, enabling precise structural modifications in target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a building block for creating specialized ligands, catalysts, and organic frameworks (MOFs/COFs) for catalytic and sensing applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	2-(2,4-Difluorophenyl)-1-(Pyridin-3-Yl)Ethan-1-One
CAS No.	1285349-13-4
Molecular Formula	C13H9F2NO
Molecular Weight	233.21 g/mol
Synonyms	1-(3-Pyridinyl)-2-(2,4-difluorophenyl)ethanone; 2,4-Difluoro-α-pyridin-3-ylacetophenone; 3-Acetylpyridine-2,4-difluorophenyl derivative; 2-(2,4-Difluorophenyl)-1-(3-pyridinyl)ethanone; 1-Pyridin-3-yl-2-(2,4-difluorophenyl)ethan-1-one; α-(2,4-Difluorophenyl)-3-pyridylmethyl ketone
EINECS	Contact for details

Quality Control

Our 2-(2,4-Difluorophenyl)-1-(Pyridin-3-Yl)Ethan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.