Description

2-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Phenyl]Butyric Acid Ethyl Ester is a high-value, advanced pharmaceutical intermediate and building block in organic synthesis. This compound matters for its role as a key precursor in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a monomer or precursor for creating advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Essential reagent in palladium-catalyzed Suzuki-Miyaura couplings for forming carbon-carbon bonds between aryl or vinyl groups.
• Chemical Biology & Proteomics: Utilized in the synthesis of probes and tags for studying biological processes and protein functions.
• Academic & Industrial R&D: A versatile starting material for method development and exploring new synthetic pathways in organic chemistry.

Basic Information

Item	Details
Product Name	2-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Phenyl]Butyric Acid Ethyl Ester
CAS No.	1282659-60-2
Molecular Formula	C18H27BO4
Molecular Weight	318.22 g/mol
Synonyms	Ethyl 2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]butanoate; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzenepropanoic Acid Ethyl Ester, α-Ethyl; 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)butyric Acid Ethyl Ester; Boric acid, cyclic ester with 2-(4-boronophenyl)butanoic acid ethyl ester; Pinacol 2-(4-(ethoxycarbonyl)butyl)phenylboronate
EINECS	Contact for details

Quality Control

Our 2-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Phenyl]Butyric Acid Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request, supporting compliance with cGMP and ICH Q7 guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere (e.g., nitrogen or argon) in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.