Description

4-Methoxy-2-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenylamine is a high-value, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides requiring specific biaryl motifs.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as OLEDs and semiconductors.
• Chemical Research & Development: Essential reagent in academic and industrial R&D labs for palladium-catalyzed cross-coupling reactions.
• Ligand and Catalyst Development: Employed in the synthesis of complex ligands for catalysis and molecular recognition.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals with high purity requirements.

Basic Information

Product Name	4-Methoxy-2-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenylamine
CAS No.	1279722-88-1
Molecular Formula	C13H20BNO3
Molecular Weight	249.12 g/mol
Synonyms	2-Amino-5-methoxyphenylboronic acid pinacol ester; 5-Methoxy-2-aminophenylboronic acid pinacol ester; 2-Amino-5-methoxybenzeneboronic acid pinacol ester; (2-Amino-5-methoxyphenyl)boronic acid pinacol ester; 4-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methoxyaniline; B-(2-Amino-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.