Description

2-(4-Iodophenyl)-4,4,6-Trimethyl-1,3,2-Dioxaborinane is a valuable organoboron building block, specifically a cyclic boronic ester, widely used in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation, which is critical for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides by introducing the iodophenyl-boronate moiety into target molecules.
• Material Science Research: Serves as a building block for constructing organic electronic materials, such as OLEDs and semiconductors, where precise conjugation is required.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the synthesis of tagged molecules and probes for studying biological processes and target engagement.
• Custom Synthesis and R&D: A versatile reagent for contract research organizations (CROs) and academic labs exploring new synthetic methodologies.

Basic Information

Product Name	2-(4-Iodophenyl)-4,4,6-Trimethyl-1,3,2-Dioxaborinane
CAS No.	1279115-53-5
Molecular Formula	C13H18BIO2
Molecular Weight	344.00 g/mol
Synonyms	4,4,6-Trimethyl-2-(4-iodophenyl)-1,3,2-dioxaborinane; 2-(4-Iodophenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane; (4-Iodophenyl)boronic acid, cyclic ester with 2,2-dimethyl-1,3-propanediol; 4-Iodophenylboronic acid neopentyl glycol ester; 4-Iodophenyl-B-neopentyl glycol ester; PINB-Iodobenzene; 4-Iodo-B-neopentyl boronate
EINECS	Contact for details

Quality Control

Our 2-(4-Iodophenyl)-4,4,6-Trimethyl-1,3,2-Dioxaborinane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (1H, 11B, 13C) and HPLC analysis, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
1H NMR	Conforms to structure
11B NMR	Conforms to structure
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.