Description

4-tert-Butyl-2-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenylamine CAS NO 1276656-57-5 is a high-purity, advanced pharmaceutical intermediate featuring a protected boronic acid ester (pinacol boronate) group. This compound is a critical building block in modern synthetic chemistry, enabling the efficient construction of complex molecules through cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as OLEDs and organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology & Proteomics: Utilized in the synthesis of molecular probes and bioconjugates for target identification and binding studies.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	4-tert-Butyl-2-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenylamine
CAS No.	1276656-57-5
Molecular Formula	C16H26BNO2
Molecular Weight	275.20 g/mol
Synonyms	2-Amino-5-tert-butylphenylboronic acid pinacol ester; 5-(tert-Butyl)-2-aminophenylboronic acid pinacol ester; 4-tert-Butyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-tert-butylaniline; 5-tert-Butyl-2-aminophenylboronic acid, pinacol ester; 2-Amino-5-tert-butylbenzeneboronic acid pinacol ester; B-(2-Amino-5-tert-butylphenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-tert-Butyl-2-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.