Description

Pyridine, 2-[[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy]Methyl]- is a high-value, functionalized pyridine derivative containing a pinacol boronate ester group, making it a versatile building block for modern synthetic chemistry. This compound is specifically engineered to serve as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is essential for R&D and production in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular assembly is critical.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides with tailored properties by introducing the pyridine-phenoxy-boronate moiety.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and conductive polymers, due to its electron-deficient pyridine core and functional handle.
• Chemical Biology & Probe Synthesis: Utilized for creating bioconjugates and molecular probes for diagnostic and research applications.
• Custom Synthesis & Contract Manufacturing: A key building block for custom synthesis projects requiring the introduction of a protected boronic acid functionality adjacent to an aromatic ether linkage.

Basic Information

Product Name	Pyridine, 2-[[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy]Methyl]-
CAS No.	1276129-55-5
Molecular Formula	C18H22BNO3
Molecular Weight	311.19 g/mol
Synonyms	2-((4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)methyl)pyridine; (4-((Pyridin-2-ylmethoxy)phenyl)boronic acid pinacol ester; 2-[[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]methyl]pyridine; 2-(4-(Pinacolatoboron)phenoxymethyl)pyridine; 4-((Pyridin-2-ylmethyl)oxy)benzeneboronic acid pinacol ester; 2-Pyridylmethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl ether
EINECS	Contact for details

Quality Control

Our production of Pyridine, 2-[[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy]Methyl]- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.