Description

2-(Benzylamino)-2-(Oxan-4-Yl)Acetonitrile is a high-value, synthetically versatile nitrile derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique molecular architecture, featuring both a benzyl-protected amine and a tetrahydropyran (oxane) ring, makes it an essential intermediate for constructing complex pharmacophores. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the construction of advanced herbicide and pesticide molecules, leveraging its structural complexity for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic and R&D Laboratories: Employed in methodological studies and as a standard for exploring new C–N bond formation and ring-opening reactions.
• Fine Chemical Production: An intermediate in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.

Basic Information

Product Name	2-(Benzylamino)-2-(Oxan-4-Yl)Acetonitrile
CAS No.	1274825-09-0
Molecular Formula	C14H18N2O
Molecular Weight	230.31 g/mol
Synonyms	2-(Benzylamino)-2-(tetrahydro-2H-pyran-4-yl)acetonitrile; 2-(Oxan-4-yl)-2-(phenylmethylamino)acetonitrile; 2-(Benzylamino)-2-(oxan-4-yl)ethanenitrile; α-(Benzylamino)-tetrahydro-2H-pyran-4-acetonitrile; 4-(Aminobenzyl)-tetrahydropyran-4-acetonitrile; (Oxan-4-yl)(benzylamino)acetonitrile; BnA-Oxane-CN; BAOA Intermediate
EINECS	Contact for details

Quality Control

Every batch of 2-(Benzylamino)-2-(Oxan-4-Yl)Acetonitrile is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and consistency for your critical R&D and scale-up processes. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and chiral integrity as per client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.