Description

4-(4-Trifluoromethyl-Phenyl)-Thiazole-2-Carbaldehyde is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity of the aldehyde group and the electronic properties imparted by the trifluoromethylphenyl moiety, enabling the construction of complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for targets in oncology, CNS disorders, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the CF3 group can enhance metabolic stability and bioavailability.
• Material Science: Serves as a building block for advanced organic electronic materials, such as ligands for OLEDs or components for nonlinear optical (NLO) applications.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and the development of chemical tools for biological study.
• Academic & Contract Research: Essential for methodological development in organic chemistry and for custom synthesis projects requiring specialized fluorinated scaffolds.

Basic Information

Product Name	4-(4-Trifluoromethyl-Phenyl)-Thiazole-2-Carbaldehyde
CAS No.	1274644-85-7
Molecular Formula	C11H6F3NOS
Molecular Weight	257.23 g/mol
Synonyms	2-Formyl-4-[4-(trifluoromethyl)phenyl]thiazole; 4-(4-Trifluoromethylphenyl)thiazole-2-carboxaldehyde; [4-(4-Trifluoromethylphenyl)-1,3-thiazol-2-yl]methanal; 4-(α,α,α-Trifluoro-p-tolyl)-2-thiazolecarboxaldehyde; 2-Thiazolecarboxaldehyde, 4-[4-(trifluoromethyl)phenyl]-; CAS 1274644-85-7
EINECS	Contact for details

Quality Control

Every batch of 4-(4-Trifluoromethyl-Phenyl)-Thiazole-2-Carbaldehyde is produced and tested under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee it meets your specific research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.