Description

7,8-Difluoro-3,4-Dihydro-1(2H)-Naphthalenone is a high-purity fluorinated organic building block of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals, where its unique difluorinated tetralone structure enables precise molecular modifications. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex, value-added molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for fluorinated organic electronic materials and liquid crystals.
• Chemical Research: Employed in academic and industrial R&D for studying fluorination effects and developing new synthetic methodologies.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	7,8-Difluoro-3,4-Dihydro-1(2H)-Naphthalenone
CAS No.	1273662-15-9
Molecular Formula	C₁₀H₈F₂O
Molecular Weight	182.17 g/mol
Synonyms	7,8-Difluoro-3,4-dihydro-2H-naphthalen-1-one; 7,8-Difluoro-1-tetralone; 7,8-Difluoro-3,4-dihydro-1(2H)-naphthalenone; 1(2H)-Naphthalenone, 7,8-difluoro-3,4-dihydro-; 7,8-Difluoro-α-tetralone; 7,8-Difluoro-3,4-dihydronaphthalen-1(2H)-one
EINECS	Contact for details

Quality Control

Our 7,8-Difluoro-3,4-Dihydro-1(2H)-Naphthalenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.