Description

5-Bromo-7-Methyl-Indan-1-One is a high-purity brominated indanone derivative, serving as a critical advanced intermediate in organic synthesis. Its unique halogenated structure makes it a valuable building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromine and ketone functionalities into target molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced herbicides and fungicides, leveraging its halogenated aromatic core.
• Material Science Research: Serves as a monomer or functional unit in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) precursors.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis and organocatalysts due to its rigid indanone scaffold.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring precise bromination and subsequent functionalization.

Basic Information

Product Name	5-Bromo-7-Methyl-Indan-1-One
CAS No.	1273609-67-8
Molecular Formula	C10H9BrO
Molecular Weight	225.08 g/mol
Synonyms	1-Indanone, 5-bromo-7-methyl-; 5-Bromo-7-methylindan-1-one; 7-Methyl-5-bromo-1-indanone; 5-Bromo-7-methyl-2,3-dihydro-1H-inden-1-one; 5-Bromo-7-methyl-1-indanone
EINECS	Contact for details

Quality Control

Our 5-Bromo-7-Methyl-Indan-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.