Description

6-Bromo-5-Fluoro-2,3-Dihydro-1H-Inden-1-One is a high-value, halogenated indanone derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular scaffold, featuring both bromine and fluorine substituents, makes it an essential building block for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity imparted by its halogenated structure.
• Material Science: Serves as a monomer or precursor for specialty polymers and advanced organic electronic materials due to its rigid, fused-ring system.
• Chemical Synthesis: Acts as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for introducing the indanone core into more complex architectures.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and the exploration of new chemical transformations.

Basic Information

Product Name	6-Bromo-5-Fluoro-2,3-Dihydro-1H-Inden-1-One
CAS No.	1273595-81-5
Molecular Formula	C9H6BrFO
Molecular Weight	229.05 g/mol
Synonyms	6-Bromo-5-fluoroindan-1-one; 5-Fluoro-6-bromo-2,3-dihydro-1H-inden-1-one; 1H-Inden-1-one, 6-bromo-5-fluoro-2,3-dihydro-; 6-Bromo-5-fluoro-2,3-dihydroinden-1-one; 1273595-81-5; 6-Bromo-5-fluoroindanone
EINECS	Contact for details

Quality Control

Our production of 6-Bromo-5-Fluoro-2,3-Dihydro-1H-Inden-1-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.