Description

4-Fluoro-5-Methyl-Indan-1-One (CAS NO 1273595-77-9) is a high-purity fluorinated indanone derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in its unique molecular scaffold, which serves as a versatile building block for constructing complex pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, contributing to the development of advanced materials with specific optical or electronic properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and natural product analogs.
• Fluorine Chemistry Studies: Acts as a model compound for investigating the effects of fluorine substitution on the reactivity and physical properties of organic molecules.

Basic Information

Product Name	4-Fluoro-5-Methyl-Indan-1-One
CAS No.	1273595-77-9
Molecular Formula	C10H9FO
Molecular Weight	164.18 g/mol
Synonyms	4-Fluoro-5-methylindan-1-one; 1-Indanone, 4-fluoro-5-methyl-; 4-Fluoro-5-methyl-2,3-dihydro-1H-inden-1-one; 5-Methyl-4-fluoroindan-1-one; 1273595-77-9; 4-Fluoro-5-methyl-1-indanone
EINECS	Contact for details

Quality Control

Our 4-Fluoro-5-Methyl-Indan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.