Description

1-(Fluoromethyl)Cyclopropanecarboxylic Acid is a high-value, fluorinated cyclopropane derivative, a key structural motif prized in modern synthetic chemistry. Its primary commercial value lies in its role as a versatile and sophisticated building block for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists working on novel active ingredients, where the introduction of the fluoromethylcyclopropyl group can significantly modulate biological activity, metabolic stability, and physicochemical properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and insecticides, where the fluorinated cyclopropane ring enhances lipophilicity and target binding.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced materials with unique surface properties.
• Ligand & Catalyst Development: Employed in the design of novel chiral ligands and organocatalysts for asymmetric synthesis applications.
• Fluorine Chemistry Building Block: A valuable synthon for introducing the metabolically stable fluoromethylcyclopropyl moiety into lead compounds during medicinal chemistry optimization.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client R&D programs.

Basic Information

Product Name	1-(Fluoromethyl)Cyclopropanecarboxylic Acid
CAS No.	1273565-75-5
Molecular Formula	C5H7FO2
Molecular Weight	118.11 g/mol
Synonyms	1-(Fluoromethyl)cyclopropanecarboxylic acid; 1-(Fluoromethyl)cyclopropane-1-carboxylic acid; Cyclopropanecarboxylic acid, 1-(fluoromethyl)-; Fluoromethylcyclopropanecarboxylic Acid; (1-(Fluoromethyl)cyclopropyl)formic acid; 1273565-75-5; FC-CA
EINECS	Contact for details

Quality Control

Our 1-(Fluoromethyl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong bases, strong oxidizing agents, and strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.