Description

1-(4-Chlorophenyl)-2-(2,4-Difluorophenyl)Ethanone is a high-purity, diaryl ethanone derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its precise molecular architecture, featuring chlorophenyl and difluorophenyl moieties, makes it an essential building block for constructing complex pharmacologically active molecules. This compound is primarily required by research institutions and pharmaceutical development companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring halogenated aromatic scaffolds.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, leveraging its difluorophenyl group for enhanced bioactivity and stability.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers with specific optical or electronic properties.
• Organic Synthesis Building Block: Employed in Suzuki, Heck, and other cross-coupling reactions to introduce complex aryl ketone functionalities into target molecules.
• Ligand Synthesis: Utilized for creating specialized ligands in catalytic systems and coordination chemistry research.

Basic Information

Product Name	1-(4-Chlorophenyl)-2-(2,4-Difluorophenyl)Ethanone
CAS No.	1271611-27-8
Molecular Formula	C14H9ClF2O
Molecular Weight	266.67 g/mol
Synonyms	2-(2,4-Difluorophenyl)-1-(4-chlorophenyl)ethanone; 1-(4-Chlorophenyl)-2-(2,4-difluorophenyl)ethan-1-one; 4'-Chloro-2',4'-difluorochalcone; (4-Chlorophenyl)(2,4-difluorophenyl)methanone (tautomeric form); p-Chloro-2,4-difluorodibenzoylmethane precursor; CAS 1271611-27-8
EINECS	Contact for details

Quality Control

Our 1-(4-Chlorophenyl)-2-(2,4-Difluorophenyl)Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee reproducible performance in your sensitive synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.