Description

1,5-Dichloro-2-Iodo-3-Methoxybenzene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and functionalized ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its halogenated benzene core.
• Material Science: Serves as a precursor for organic electronic materials, including charge-transport molecules and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) due to the reactive iodine and chlorine substituents.
• Chemical Biology: Utilized in the synthesis of molecular probes and tags for imaging and diagnostic applications.
• Ligand Synthesis: Building block for creating sophisticated chelating ligands used in homogeneous catalysis.

Basic Information

Product Name	1,5-Dichloro-2-Iodo-3-Methoxybenzene
CAS No.	1271523-34-2
Molecular Formula	C7H5Cl2IO
Molecular Weight	302.93 g/mol
Synonyms	3-Methoxy-1,5-dichloro-2-iodobenzene; 2-Iodo-1,5-dichloro-3-methoxybenzene; 1,5-Dichloro-2-iodo-3-methoxybenzene; Benzene, 1,5-dichloro-2-iodo-3-methoxy-; 1271523-34-2
EINECS	Contact for details

Quality Control

Our 1,5-Dichloro-2-Iodo-3-Methoxybenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability and consistency for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.