Description

1-[3-(Trifluoromethoxy)Phenyl]But-3-Enylamine is a high-purity, advanced pharmaceutical intermediate featuring a unique trifluoromethoxy-substituted aromatic structure. This compound is of significant commercial importance for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate its specific fluorinated motif into new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in CNS-targeted therapies and metabolic disease research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and material science applications.
• Fluorinated Compound Library: An essential component for constructing diverse screening libraries in medicinal chemistry for hit identification and lead optimization.
• Chemical Biology Probes: Utilized in the design of molecular probes to study enzyme function and biological pathways.
• Advanced Material Precursor: Potential use in the synthesis of monomers for specialty polymers with tailored properties.

Basic Information

Product Name	1-[3-(Trifluoromethoxy)Phenyl]But-3-Enylamine
CAS No.	1270568-66-5
Molecular Formula	C11H12F3NO
Molecular Weight	231.21 g/mol
Synonyms	3-(Trifluoromethoxy)benzene-1-(3-butenylamine); 1-[3-(Trifluoromethoxy)phenyl]-3-buten-1-amine; 3-[(3-Buten-1-yl)amino]phenyl trifluoromethyl ether; But-3-en-1-yl-[3-(trifluoromethoxy)phenyl]amine; α-Methyl-3-(trifluoromethoxy)phenethylamine derivative; 3-(3-Butenylamino)phenyl trifluoromethyl ether
EINECS	Contact for details

Quality Control

Our 1-[3-(Trifluoromethoxy)Phenyl]But-3-Enylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring high-purity intermediates under GMP or ISO guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid / solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.