Description

1-(2-Chloro-3-Fluorophenyl)Ethanamine is a high-purity fluorinated aromatic amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated phenyl ring structure imparts specific biological activity and metabolic stability. Pharmaceutical, agrochemical, and specialty chemical R&D teams need this material to synthesize new drug candidates, crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel small-molecule drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine and chlorine substituents for enhanced efficacy.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein function.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	1-(2-Chloro-3-Fluorophenyl)Ethanamine
CAS No.	1270482-67-1
Molecular Formula	C8H9ClFN
Molecular Weight	173.61 g/mol
Synonyms	1-(2-Chloro-3-fluorophenyl)ethan-1-amine; 1-(2-Chloro-3-fluorophenyl)ethylamine; α-Methyl-2-chloro-3-fluoroaniline; 2-Chloro-3-fluoro-α-methylbenzylamine; 1-(2-Chloro-3-fluorophenyl)ethanamine hydrochloride (salt form); 2-Chloro-3-fluoro-α-methylbenzenemethanamine
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-3-Fluorophenyl)Ethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can be aligned with research-grade or cGMP standards to meet the specific requirements of pharmaceutical and agrochemical development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.