Description

1-(5-Bromo-2-Fluoro-Phenyl)-2,2,2-Trifluoro-Ethylamine is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated aromatic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted therapies. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry for central nervous system (CNS) and oncology applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting neurological disorders and cancer.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides due to its fluorinated and brominated phenyl group.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals, leveraging its aromatic and fluorine content.
• Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce functionalized aromatic systems into larger molecules.
• Fluorine Chemistry Research: A valuable substrate for studying the effects of multiple fluorine atoms on molecular reactivity and biological activity.

Basic Information

Product Name	1-(5-Bromo-2-Fluoro-Phenyl)-2,2,2-Trifluoro-Ethylamine
CAS No.	1270452-52-2
Molecular Formula	C8H6BrF4N
Molecular Weight	272.04 g/mol
Synonyms	α-(Trifluoromethyl)-5-bromo-2-fluoro-benzeneethanamine; 2,2,2-Trifluoro-1-(5-bromo-2-fluorophenyl)ethan-1-amine; 1-(5-Bromo-2-fluorophenyl)-2,2,2-trifluoroethanamine; 5-Bromo-2-fluoro-α-(trifluoromethyl)benzylamine; (5-Bromo-2-fluorophenyl)(trifluoromethyl)methylamine; 2,2,2-Trifluoro-1-(5-bromo-2-fluorophenyl)ethylamine; CAS 1270452-52-2
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-2-Fluoro-Phenyl)-2,2,2-Trifluoro-Ethylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP and ISO standards to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, the container should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.