Description

1-Cyclopentyl-2,2,2-trifluoroethan-1-amine is a high-value, fluorinated amine building block characterized by its cyclopentyl and trifluoroethyl motifs. This compound matters for its role in introducing lipophilicity and metabolic stability into target molecules, which is critical for developing advanced pharmaceuticals and agrochemicals. It is primarily needed by research and development chemists in the pharmaceutical industry for medicinal chemistry and drug discovery programs, as well as by agrochemical manufacturers for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disease targets.
• Medicinal Chemistry Building Block: Used to incorporate the cyclopentyl and trifluoroethyl groups into lead compounds to optimize their potency, selectivity, and pharmacokinetic properties.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Utilized in organometallic chemistry for the synthesis of novel chiral ligands and catalysts for asymmetric synthesis.
• Material Science Research: Investigated as a monomer or modifier for creating specialty polymers with unique surface properties and chemical resistance.
• Fluorine Chemistry Studies: Employed in academic and industrial research to study the effects of fluorine substitution on chemical reactivity and physical properties.

Basic Information

Product Name	1-Cyclopentyl-2,2,2-trifluoroethan-1-amine
CAS No.	1270447-57-8
Molecular Formula	C7H12F3N
Molecular Weight	167.17 g/mol
Synonyms	1-Cyclopentyl-2,2,2-trifluoroethylamine; α-(Trifluoromethyl)cyclopentylmethylamine; (1-Cyclopentyl-2,2,2-trifluoroethyl)amine; 2,2,2-Trifluoro-1-cyclopentylethanamine; Cyclopentyl(trifluoromethyl)methylamine; 1-Amino-2,2,2-trifluoro-1-cyclopentylethane
EINECS	Contact for details

Quality Control

Our 1-Cyclopentyl-2,2,2-trifluoroethan-1-amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic); keep container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.