Description

Phenylalanine, 2-Chloro-4-Methyl- CAS NO 1270310-78-5 is a halogenated derivative of the essential amino acid phenylalanine, serving as a sophisticated chiral building block and key synthetic intermediate. This compound matters for its role in introducing specific structural motifs into target molecules, enabling the development of novel compounds with tailored biological or chemical properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, peptide research, and the synthesis of fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Peptide Modification: Used to incorporate modified phenylalanine residues into synthetic peptides, altering their stability, receptor binding affinity, or metabolic profile.
• Agrochemical Synthesis: Serves as a building block in the creation of novel herbicides, fungicides, or plant growth regulators that require specific halogenated amino acid structures.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to investigate metabolic pathways involving aromatic amino acids.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex organic molecules, dyes, and specialty chemicals where precise halogen substitution is critical.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands used in asymmetric catalysis, enhancing the enantioselectivity of synthetic transformations.

Basic Information

Item	Detail
Product Name	Phenylalanine, 2-Chloro-4-Methyl-
CAS No.	1270310-78-5
Molecular Formula	C10H12ClNO2
Molecular Weight	213.66 g/mol
Synonyms	2-Chloro-4-methyl-DL-phenylalanine; (RS)-2-Amino-3-(2-chloro-4-methylphenyl)propanoic acid; 2-Chloro-4-methylphenylalanine; 4-Methyl-2-chlorophenylalanine; α-Amino-2-chloro-4-methylbenzenepropanoic acid; DL-2-Chloro-4-methylphenylalanine; (±)-2-Chloro-4-methylphenylalanine
EINECS	Contact for details

Quality Control

Our Phenylalanine, 2-Chloro-4-Methyl- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.