Description

9-Bromo-4,5-Dihydro-1H-Benzo[B]Azepin-2(3H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its brominated benzazepinone core structure. This compound is a critical building block in modern organic synthesis, enabling the construction of complex molecules with potential biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex heterocyclic compounds for drug discovery and development programs.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and the creation of targeted molecular libraries.
• Organic Synthesis Building Block: The bromine atom provides a reactive site for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and enzyme functions.
• Agrochemical Research: Potential intermediate in the research and development of novel crop protection agents and pesticides.
• Material Science Applications: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	9-Bromo-4,5-Dihydro-1H-Benzo[B]Azepin-2(3H)-One
CAS No.	1269293-40-4
Molecular Formula	C10H10BrNO
Molecular Weight	240.10 g/mol
Synonyms	9-Bromo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-2-one; 9-Bromo-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one; 9-Bromo-2,3,4,5-tetrahydro-1H-2-benzazepin-2-one; 9-Bromotetrahydro-1H-2-benzazepin-2-one; 9-Bromo-1,2,3,5-tetrahydro-2-benzazepin-2-one; 9-Bromo-4,5-dihydro-1H-2-benzazepin-2(3H)-one
EINECS	Contact for details

Quality Control

Our 9-Bromo-4,5-Dihydro-1H-Benzo[B]Azepin-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for pharmaceutical R&D and cGMP intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.