Description

1-(4-Fluorophenyl)-5-(Thiophen-2-Yl)-1H-Pyrazole is a high-purity, heterocyclic organic compound featuring a pyrazole core substituted with fluorophenyl and thiophene groups. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in therapeutic areas targeting the central nervous system and metabolic diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its privileged heterocyclic scaffold.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new-generation pesticides and herbicides.
• Material Science: Investigated as a monomer or functional component in the development of organic electronic materials and specialty polymers.
• Chemical Synthesis: Employed as a versatile reagent in cross-coupling reactions and other advanced organic transformations to create complex molecular architectures.

Basic Information

Product Name	1-(4-Fluorophenyl)-5-(Thiophen-2-Yl)-1H-Pyrazole
CAS No.	1269291-65-7
Molecular Formula	C13H9FN2S
Molecular Weight	244.29 g/mol
Synonyms	1-(4-Fluorophenyl)-5-(thiophen-2-yl)-1H-pyrazole; 5-(Thiophen-2-yl)-1-(4-fluorophenyl)-1H-pyrazole; 1H-Pyrazole, 1-(4-fluorophenyl)-5-(2-thienyl)-; 1-(p-Fluorophenyl)-5-(2-thienyl)pyrazole; 1269291-65-7; 5-(Thiophen-2-yl)-1-(4-fluorophenyl)pyrazole
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorophenyl)-5-(Thiophen-2-Yl)-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	≤ 2.0% total
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.