Description

1-(tert-Butoxycarbonyl)Cyclopropanecarboxylic Acid is a versatile and high-purity chemical building block, primarily used as a key intermediate in advanced organic synthesis. Its value lies in the protected carboxylic acid and cyclopropane functionalities, which are crucial for constructing complex molecular architectures with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially those containing cyclopropane rings, which are valuable in medicinal chemistry for modulating metabolic stability and biological activity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropane moiety can enhance potency and environmental profile.
• Peptide Chemistry: Serves as a protected amino acid derivative or a carboxylic acid component in peptide coupling reactions for constructing modified peptide sequences.
• Material Science Research: Employed as a monomer or precursor for synthesizing specialized polymers and functional materials with unique thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological processes and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-(tert-Butoxycarbonyl)Cyclopropanecarboxylic Acid
CAS No.	1268842-79-0
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	1-Boc-cyclopropanecarboxylic acid; Cyclopropanecarboxylic acid, 1-[(1,1-dimethylethoxy)carbonyl]-; 1-(Boc)cyclopropanecarboxylic Acid; tert-Butyl 1-carboxycyclopropylcarbamate; 1-[(tert-Butoxycarbonyl)]cyclopropanecarboxylic Acid; 1-N-Boc-cyclopropanecarboxylic acid; Boc-Cyclopropane-COOH; (1-((tert-Butoxycarbonyl))cyclopropyl)formic acid
EINECS	Contact for details

Quality Control

Our 1-(tert-Butoxycarbonyl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent identity. Certificates of Analysis (COA) with detailed specifications are provided for each lot, supporting its use in GMP (Good Manufacturing Practice) environments for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.