Description

2,2,2-Trifluoro-1-(Piperidin-4-Yl)Ethane-1,1-Diol is a high-value fluorinated piperidine derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its unique structure, combining a trifluoromethyl group with a piperidine scaffold, makes it essential for modulating the physicochemical and metabolic properties of target molecules. This compound is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functional additive in the creation of specialty polymers and fluorinated materials.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to introduce fluorine atoms, improving a compound's lipophilicity, metabolic stability, and bioavailability.
• Chemical Research: A versatile reagent for constructing complex heterocyclic systems and for introducing fluorinated motifs in organic synthesis.

Basic Information

Item	Details
Product Name	2,2,2-Trifluoro-1-(Piperidin-4-Yl)Ethane-1,1-Diol
CAS No.	1268520-17-7
Molecular Formula	C7H12F3NO2
Molecular Weight	199.17 g/mol
Synonyms	2,2,2-Trifluoro-1-(4-piperidinyl)-1,1-ethanediol; 1,1,1-Trifluoro-2,2-bis(hydroxy)-4-piperidinylethane; 4-(1,1,1-Trifluoro-2,2-dihydroxyethyl)piperidine; 2,2,2-Trifluoro-1-(piperidin-4-yl)ethane-1,1-diol; Trifluoromethyl piperidine diol; TFPD; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(Piperidin-4-Yl)Ethane-1,1-Diol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) documenting purity, impurities, and other critical parameters are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.