Description

4-sec-Butylphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative, a crucial intermediate in modern synthetic organic chemistry. Its value lies in its enhanced stability compared to the free boronic acid, making it ideal for demanding cross-coupling reactions where moisture sensitivity is a concern. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key building block for creating biaryl and heterobiaryl structures, which are core scaffolds in many active pharmaceutical ingredients (APIs) and agrochemicals.
• Pharmaceutical Intermediate Synthesis: Used in the research and scale-up production of novel drug candidates, particularly in oncology, CNS, and antiviral therapeutic areas.
• Agrochemical Active Ingredient Development: Employed to synthesize advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Utilized in the development of organic electronic materials, such as polymers for OLEDs and OFETs, where precise molecular structure is critical.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes for target identification and validation.

Basic Information

Product Name	4-sec-Butylphenylboronic Acid Pinacol Ester
CAS No.	1268242-41-6
Molecular Formula	C₁₆H₂₅BO₂
Molecular Weight	260.18 g/mol
Synonyms	4-(sec-Butyl)benzeneboronic acid pinacol ester; 4-(1-Methylpropyl)benzeneboronic acid pinacol ester; (4-sec-Butylphenyl)boronic acid pinacol ester; B-[4-(1-Methylpropyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-sec-Butylbenzeneboronic acid pinacol ester; Pinacol 4-(sec-butyl)phenylboronate; 4-(sec-Butyl)phenylboronic acid, pinacol ester; CAS 1268242-41-6
EINECS	Contact for details

Quality Control

Our 4-sec-Butylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or when opening the primary container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.