Description

4-Formyl-3-Nitrophenylboronic Acid, Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative. This compound is a critical protected boronic acid building block, essential for Suzuki-Miyaura cross-coupling reactions in advanced organic synthesis. It is primarily used by pharmaceutical R&D and agrochemical laboratories for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring biaryl linkages.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with specific targeting properties.
• Material Science Research: Used in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological processes and enzyme inhibition.
• Academic & Contract Research: Essential reagent for methodological development and complex molecule construction in academic and CRO settings.

Basic Information

Product Name	4-Formyl-3-Nitrophenylboronic Acid, Pinacol Ester
CAS No.	1268163-62-7
Molecular Formula	C13H16BNO5
Molecular Weight	277.08 g/mol
Synonyms	3-Nitro-4-formylphenylboronic acid pinacol ester; (3-Nitro-4-formylphenyl)boronic acid pinacol ester; 4-Formyl-3-nitrobenzeneboronic acid pinacol ester; Pinacol (3-nitro-4-formylphenyl)boronate; 2-(3-Nitro-4-formylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Every batch of our 4-Formyl-3-Nitrophenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. We guarantee high chemical purity and lot-to-lot consistency through comprehensive analytical techniques including HPLC, NMR, and MS. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.