Description

1-(4-Fluorophenyl)-2-(Piperidin-1-Yl)Ethane-1,2-Dione is a high-purity organic building block featuring a fluorinated aromatic ring and a diketone-piperidine scaffold. This compound matters as a critical intermediate for pharmaceutical research and development, enabling the synthesis of novel active molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the development of potential drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and pesticides, leveraging the bioactivity of the fluorophenyl moiety.
• Chemical Biology Probe Development: Serves as a scaffold for creating tool compounds to study enzyme function and protein-ligand interactions.
• Material Science Precursor: Potential building block for organic electronic materials and specialty polymers due to its conjugated diketone system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Institutional Research: Used in university and government labs for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Item	Details
Product Name	1-(4-Fluorophenyl)-2-(Piperidin-1-Yl)Ethane-1,2-Dione
CAS No.	1268138-60-8
Molecular Formula	C13H14FNO2
Molecular Weight	235.26 g/mol
Synonyms	1-(4-Fluorophenyl)-2-(piperidin-1-yl)ethane-1,2-dione; 2-Oxo-1-(4-fluorophenyl)-2-(piperidin-1-yl)ethan-1-one; 4-Fluoro-α-oxo-N-piperonylbenzeneacetamide (obsolete); 1-(4-Fluorobenzoyl)-2-piperidinylethanedione; FPPE; (4-Fluorophenyl)(piperidin-1-yl)glyoxal; 1268138-60-8; Glyoxal, (4-fluorophenyl)-, 1-(N-piperidyl)-
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorophenyl)-2-(Piperidin-1-Yl)Ethane-1,2-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under GMP-like or research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.