Description

3-(Pentafluorosulfur)-Dl-Phenylalanine CAS NO 1266124-50-8 is a specialized fluorinated amino acid derivative, distinguished by its unique pentafluorosulfur (SF5) functional group. This compound is a critical building block in advanced pharmaceutical research and agrochemical development, offering enhanced metabolic stability and lipophilicity to target molecules. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for creating novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery.
• Agrochemical Research: Used in the synthesis of advanced herbicides and pesticides, where the SF5 group can improve activity and environmental persistence.
• Peptide Modification: Incorporated into peptide chains to study structure-activity relationships (SAR) and enhance peptide stability against enzymatic degradation.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals with unique electronic and optical properties.
• Bioconjugation & Probe Development: Employed in creating chemical probes and bioconjugates for diagnostic imaging and biochemical assays.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists exploring new reactions and properties of organofluorine compounds.

Basic Information

Product Name	3-(Pentafluorosulfur)-Dl-Phenylalanine
CAS No.	1266124-50-8
Molecular Formula	C9H8F5NO2S
Molecular Weight	289.22 g/mol
Synonyms	DL-3-(Pentafluorosulfanyl)phenylalanine; 3-(SF5)-DL-Phenylalanine; (RS)-2-Amino-3-[3-(pentafluoro-λ6-sulfanyl)phenyl]propanoic acid; Pentafluorosulfanylphenylalanine; SF5-Phenylalanine; 3-(Pentafluoro-λ6-sulfanyl)-DL-phenylalanine; Amino acid SF5 derivative; 1266124-50-8
EINECS	Contact for details

Quality Control

Our 3-(Pentafluorosulfur)-Dl-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.