Description

2-(4,4-Difluorobutyl)Isoindoline-1,3-Dione is a specialized fluorinated phthalimide derivative, a high-value building block in advanced organic synthesis. Its core value lies in introducing a difluorobutyl side chain, which can significantly alter the physicochemical and metabolic properties of target molecules. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly where fluorination is used to enhance metabolic stability, bioavailability, or membrane permeability.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, or insecticides, leveraging the fluorine moiety for improved efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialized polymers, such as polyimides, with potential applications in electronics or coatings.
• Ligand and Catalyst Development: The phthalimide group can act as a coordinating moiety or be further modified to create novel ligands for catalytic systems.
• Fluorine Chemistry Research: A valuable substrate for studying the reactivity and incorporation of fluorinated alkyl chains into complex heterocyclic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	2-(4,4-Difluorobutyl)Isoindoline-1,3-Dione
CAS No.	1265341-14-7
Molecular Formula	C₁₂H₁₁F₂NO₂
Molecular Weight	239.22 g/mol
Synonyms	N-(4,4-Difluorobutyl)phthalimide; 1,3-Isoindolinedione, 2-(4,4-difluorobutyl)-; 2-(4,4-Difluorobutyl)-1H-isoindole-1,3(2H)-dione; 4,4-Difluorobutylphthalimide; Phthalimide, N-(4,4-difluorobutyl)-; N-(4,4-Difluorobutyl)-1,2-benzenedicarboximide
EINECS	Contact for details

Quality Control

Our 2-(4,4-Difluorobutyl)Isoindoline-1,3-Dione is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and moisture. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.