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(4'-Cyano-[1,1'-Biphenyl]-2-Yl)Boronic Acid CAS NO 1265312-65-9


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CAS No.:1265312-65-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(4'-Cyano-[1,1'-Biphenyl]-2-Yl)Boronic Acid is a high-purity, functionalized boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and organic electronics industries who require reliable, high-quality intermediates for complex molecule synthesis.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drug candidates targeting central nervous system (CNS) disorders and oncology.
  • Agrochemical Synthesis: Used to construct complex molecular scaffolds for novel herbicides, fungicides, and insecticides.
  • Material Science Research: Building block for creating organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) for electronic and photonic applications.
  • Cross-Coupling Reactions: Primarily employed in Suzuki-Miyaura cross-coupling to form biaryl and heterobiaryl structures with high efficiency and selectivity.
  • Chemical Biology Probes: Utilized in the development of molecular probes and sensors due to its reactive boronic acid group.
  • Polymer Chemistry: Monomer or functionalization agent for creating specialty polymers with tailored properties.

Basic Information

Product Name (4'-Cyano-[1,1'-Biphenyl]-2-Yl)Boronic Acid
CAS No. 1265312-65-9
Molecular Formula C₁₄H₁₀BNO₂
Molecular Weight 235.05 g/mol
Synonyms 2-(4'-Cyanobiphenyl-4-yl)boronic acid; [1,1'-Biphenyl]-2-boronic acid, 4'-cyano-; 4'-Cyano-2-biphenylboronic acid; 2-(4-Cyanophenyl)phenylboronic acid; (2-(4'-Cyanobiphenyl-4-yl))boronic acid; Boronic acid, B-[2-(4-cyanophenyl)phenyl]-; 4-Cyanobiphenyl-2-boronic acid
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Quality Control

Every batch of (4'-Cyano-[1,1'-Biphenyl]-2-Yl)Boronic Acid undergoes rigorous analytical testing to ensure it meets the stringent purity requirements for research and commercial synthesis. Our quality assurance protocols are designed to guarantee batch-to-batch consistency and reliability. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥97.0%
Water Content (KF) ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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