Description

n-Boc-D-Allothreoninal Acetonide is a high-purity, protected amino acid derivative essential for advanced peptide synthesis and pharmaceutical research. This compound serves as a critical chiral building block, enabling the precise construction of complex molecules with defined stereochemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries for developing novel therapeutic agents and bioactive peptides.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel peptide-based drugs and protease inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate the D-allothreonine residue with orthogonal protecting groups (Boc and acetonide).
• Chemical Biology Research: Employed in the study of protein structure-function relationships and the development of enzyme substrates or inhibitors.
• Fine Chemical Production: Serves as a building block for custom-designed molecules in agrochemical and material science research.
• Process Development: Used in scaling up synthetic routes for active pharmaceutical ingredients (APIs) requiring high stereochemical purity.

Basic Information

Product Name	n-Boc-D-Allothreoninal Acetonide
CAS No.	1264520-06-0
Molecular Formula	C14H25NO5
Molecular Weight	287.35 g/mol
Synonyms	(2R,3S)-2-[(tert-Butoxycarbonyl)amino]-3-hydroxybutanal 2,3-acetonide; D-allo-Threoninal, N-Boc-, acetonide; tert-Butyl ((2R,3S)-3-hydroxy-1,1-dimethyl-1,3-dihydro-2H-cyclopenta[b]furan-2-yl)carbamate; N-Boc-D-allothreoninal acetonide; Boc-D-allo-Thr(Acetonide)-H; (2R,3S)-2-((tert-Butoxycarbonyl)amino)-3-hydroxybutanal cyclic acetonide
EINECS	Contact for details

Quality Control

Our n-Boc-D-Allothreoninal Acetonide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.