Description

2-Phenylpyrimidine-5-Boronic Acid is a high-value boronic acid derivative and a crucial building block in modern synthetic chemistry. Its primary value lies in its role as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop active pharmaceutical ingredients (APIs), advanced crop protection agents, and organic electronic materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and other advanced functional materials.
• Chemical Research: A versatile reagent in academic and industrial R&D for constructing complex molecular architectures via palladium-catalyzed cross-coupling.
• Ligand Synthesis: Used to prepare specialized boronic acid-based ligands for catalysis and molecular recognition applications.

Basic Information

Product Name	2-Phenylpyrimidine-5-Boronic Acid
CAS No.	1264510-78-2
Molecular Formula	C10H9BN2O2
Molecular Weight	200.01 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-phenylpyrimidine; 2-Phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine; 2-Phenylpyrimidin-5-ylboronic acid; 2-Phenyl-5-pyrimidineboronic acid; (2-Phenylpyrimidin-5-yl)boronic acid; 2-Phenyl-5-boronopyrimidine; B-(2-Phenyl-5-pyrimidinyl)boronic acid
EINECS	Contact for details

Quality Control

Our 2-Phenylpyrimidine-5-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.