Description

4,4,5,5-Tetramethyl-2-(1-Methylpiperid-4-Yl)-1,3,2-Dioxaborolane, 97% is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. This compound is a critical reagent in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams, agrochemical manufacturers, and advanced material scientists for developing new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boron-containing reagent for forming carbon-carbon bonds between aryl or vinyl halides and boronic acids/esters.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly for introducing complex amine-containing fragments.
• Agrochemical Development: Serves as a building block for creating new herbicides, fungicides, and insecticides with tailored properties.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Medicinal Chemistry & Drug Discovery: Facilitates the rapid exploration of chemical space through parallel synthesis and library development for lead optimization.
• Chemical Biology Probes: Used to create tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(1-Methylpiperid-4-Yl)-1,3,2-Dioxaborolane, 97%
CAS No.	1264198-72-2
Molecular Formula	C14H28BNO2
Molecular Weight	253.19 g/mol
Synonyms	1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine; 2-(1-Methyl-4-piperidinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine; (1-Methylpiperidin-4-yl)boronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methylpiperidine; N-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(1-Methylpiperid-4-Yl)-1,3,2-Dioxaborolane, 97% is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This material is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.