Description

6-(3-Methyl-1H-Pyrazol-1-Yl)Pyridine-2-Boronic Acid is a high-value boronic acid derivative and a key building block in modern synthetic chemistry, particularly for cross-coupling reactions. Its molecular structure, featuring both a pyridine and a pyrazole moiety, makes it an essential intermediate for constructing complex heterocyclic systems. This compound is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugates for studying biological pathways and protein interactions.
• Ligand Synthesis for Catalysis: Used to prepare sophisticated nitrogen-containing ligands for transition metal catalysts.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	6-(3-Methyl-1H-Pyrazol-1-Yl)Pyridine-2-Boronic Acid
CAS No.	1264148-03-9
Molecular Formula	C9H10BN3O2
Molecular Weight	203.01 g/mol
Synonyms	6-(3-Methyl-1H-pyrazol-1-yl)pyridine-2-boronic acid; 2-Borono-6-(3-methyl-1H-pyrazol-1-yl)pyridine; 6-(3-Methylpyrazol-1-yl)pyridine-2-boronic acid; 6-(3-Methyl-1H-pyrazol-1-yl)-2-pyridineboronic acid; (6-(3-Methyl-1H-pyrazol-1-yl)pyridin-2-yl)boronic acid; B-[6-(3-Methyl-1H-pyrazol-1-yl)-2-pyridinyl]boronic acid
EINECS	Contact for details

Quality Control

Our production of 6-(3-Methyl-1H-Pyrazol-1-Yl)Pyridine-2-Boronic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Typical 98-99%)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.