Description

2,2-Dimethyl-1-[4-(Trifluoromethoxy)Phenyl]Propan-1-One is a specialized organic compound featuring a trifluoromethoxy-substituted aromatic ketone structure. This molecule is valued for its unique combination of steric bulk and fluorine-containing functional groups, which are critical for modulating the physical and biological properties of advanced materials and active pharmaceutical ingredients. It serves as a key synthetic intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with enhanced stability and activity.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethoxy group can improve lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing compounds used in electronic displays and organic light-emitting diodes (OLEDs) due to its ability to influence electronic properties.
• Polymer & Resin Modifier: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Organic Synthesis & R&D: A versatile reagent in academic and industrial research laboratories for constructing complex molecular architectures, including heterocycles and fluorinated analogs.

Basic Information

Product Name	2,2-Dimethyl-1-[4-(Trifluoromethoxy)Phenyl]Propan-1-One
CAS No.	1263313-09-2
Molecular Formula	C₁₂H₁₃F₃O₂
Molecular Weight	246.23 g/mol
Synonyms	1-[4-(Trifluoromethoxy)phenyl]-2,2-dimethylpropan-1-one; 2,2-Dimethyl-1-(4-trifluoromethoxyphenyl)propan-1-one; α,α-Dimethyl-4-(trifluoromethoxy)phenylacetone; 4-(Trifluoromethoxy)phenyl Pivalophenone; Pivalophenone, 4'-(trifluoromethoxy)-; Trifluoromethoxy Pivalophenone
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-1-[4-(Trifluoromethoxy)Phenyl]Propan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.