Description

Methyl 3-(Aminomethyl)-4-(Trifluoromethoxy)Benzoate is a high-value, multifunctional aromatic building block featuring both an aminomethyl and a trifluoromethoxy substituent. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its unique structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group for enhanced efficacy and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or metal-organic frameworks (MOFs) in asymmetric catalysis and material science.
• Peptidomimetics and Bio-conjugation: The reactive aminomethyl group facilitates its incorporation into peptide backbones or its use as a linker for bioconjugation in probe and drug delivery system development.
• Fluorinated Liquid Crystal Materials: Acts as a building block for fluorinated aromatic cores in the synthesis of advanced liquid crystal displays (LCDs).
• Custom Synthesis and Contract Manufacturing: Supplied for custom synthesis projects requiring a specific, high-purity fluorinated benzoate derivative.

Basic Information

Product Name	Methyl 3-(Aminomethyl)-4-(Trifluoromethoxy)Benzoate
CAS No.	1263280-11-0
Molecular Formula	C10H10F3NO3
Molecular Weight	249.19 g/mol
Synonyms	Methyl 3-(aminomethyl)-4-(trifluoromethoxy)benzoate; Benzoic acid, 3-(aminomethyl)-4-(trifluoromethoxy)-, methyl ester; 3-(Aminomethyl)-4-(trifluoromethoxy)benzoic acid methyl ester; Methyl 3-aminomethyl-4-trifluoromethoxybenzoate; 4-(Trifluoromethoxy)-3-(aminomethyl)benzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-(Aminomethyl)-4-(Trifluoromethoxy)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.