Description

3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Acrylic Acid Ethyl Ester is a high-value, versatile boronic ester building block designed for advanced organic synthesis. This compound is essential for facilitating efficient carbon-carbon bond formation, particularly in cross-coupling reactions, due to its reactive vinyl boronate functionality. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in creating novel active ingredients for crop protection products.
• Material Science & Polymer Chemistry: Serves as a monomer or functionalization agent for synthesizing specialty polymers and advanced materials.
• Liquid Crystal & OLED Material Development: A precursor for constructing conjugated molecular frameworks used in electronic displays.
• Chemical Biology & Probe Synthesis: Utilized for labeling and modifying biomolecules due to its bio-orthogonal reactivity.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Acrylic Acid Ethyl Ester
CAS No.	1263187-14-9
Molecular Formula	C11H19BO4
Molecular Weight	226.08 g/mol
Synonyms	Ethyl 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)acrylate; 2-Propenoic acid, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester; Ethyl (E)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)acrylate; Vinylboronic acid pinacol ester, ethyl ester derivative; Boric acid, B-[2-(ethoxycarbonyl)ethenyl]-, 2,2-dimethyltrimethylene ester
EINECS	Contact for details

Quality Control

Our 3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Acrylic Acid Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR, and GC analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis and maintain optimal reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (GC/HPLC)	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.