Description

(±)-Threo-Isopropylphenidate (Hydrochloride) is a high-purity synthetic organic compound belonging to the phenidate class. This material is of significant interest for advanced research and development in neuropharmacology and medicinal chemistry. It serves as a critical intermediate or reference standard for researchers and developers in the pharmaceutical and life sciences sectors, particularly those investigating central nervous system (CNS) activity.

Application

• Pharmaceutical Research & Development (R&D): Primary use as a reference standard or analytical control substance in method development and validation.
• Medicinal Chemistry: Serves as a key synthetic intermediate or building block for the creation of novel chemical entities targeting neurological pathways.
• Preclinical Studies: Utilized in in vitro and in vivo studies to investigate pharmacological profiles, structure-activity relationships (SAR), and metabolic pathways.
• Analytical Testing: Employed as a certified reference material (CRM) in high-performance liquid chromatography (HPLC), mass spectrometry (MS), and other analytical techniques for accurate quantification.
• Academic Research: Used in university and institutional labs for fundamental neuroscience and biochemical research projects.
• Contract Research Organizations (CROs): Supplied to CROs conducting specialized bioanalytical and pharmacological testing services for client projects.

Basic Information

Product Name	(±)-Threo-Isopropylphenidate (Hydrochloride)
CAS No.	1262795-94-7
Molecular Formula	C16H23NO2 • HCl
Molecular Weight	297.82 g/mol (Hydrochloride salt)
Synonyms	IPH (Hydrochloride); Isopropylphenidate HCl; (±)-threo-Methyl 2-(piperidin-2-yl)-2-(4-isopropylphenyl)acetate hydrochloride; DL-threo-Isopropylphenidate hydrochloride; IPPD HCl; 4-isopropyl-Methylphenidate hydrochloride; N-Methyl-α-phenyl-2-piperidineacetate isopropyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our (±)-Threo-Isopropylphenidate (Hydrochloride) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the exacting standards required for research applications. A detailed Certificate of Analysis (COA) providing batch-specific results is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	Specified ratio of (±)-threo isomers
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.