Description

3-(3-Fluorophenyl)-1,2,4-Oxadiazole is a high-value fluorinated heterocyclic building block, identified by CAS NO 1262412-46-3. This compound is prized for its role as a key synthetic intermediate in advanced organic chemistry, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who require precise, high-purity intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders, due to the bioisosteric properties of the 1,2,4-oxadiazole ring.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom and heterocyclic core can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic materials with tailored electronic or optical properties.
• Chemical Biology Probe: Employed in medicinal chemistry to create molecular probes for studying enzyme function and receptor binding, leveraging its fluorinated aromatic structure.
• Ligand Synthesis for Catalysis: Used to construct novel nitrogen-containing ligands for transition metal catalysts used in cross-coupling and other synthetic transformations.

Basic Information

Product Name	3-(3-Fluorophenyl)-1,2,4-Oxadiazole
CAS No.	1262412-46-3
Molecular Formula	C8H5FN2O
Molecular Weight	164.14 g/mol
Synonyms	3-(3-Fluorophenyl)-1,2,4-oxadiazole; 1,2,4-Oxadiazole, 3-(3-fluorophenyl)-; 3-(3-Fluorophenyl)-1,2,4-oxadiazole; 3-(3-Fluorophenyl)-[1,2,4]oxadiazole; 3-(m-Fluorophenyl)-1,2,4-oxadiazole; 3-(3-Fluorophenyl)-1,2,4-oxadiazole (CAS 1262412-46-3); 3-(3-Fluorophenyl)-1,2,4-oxadiazole, 95%+; 3-(3-Fluorophenyl)-1,2,4-oxadiazole (Fluorinated Oxadiazole)
EINECS	Contact for details

Quality Control

Our 3-(3-Fluorophenyl)-1,2,4-Oxadiazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids, strong bases, and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.