Description

24-Hydroxy-Licoricesaponin A3 is a bioactive triterpenoid saponin derivative, a key marker compound for the standardization and quality control of licorice (Glycyrrhiza) extracts. This high-purity reference standard is critical for ensuring the potency, consistency, and efficacy of phytopharmaceutical and nutraceutical formulations. It is primarily sought by manufacturers and research institutions in the pharmaceutical, dietary supplement, and cosmetic industries for analytical, research, and development purposes.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantitative and qualitative analysis of licorice-based drugs and herbal preparations.
• Nutraceutical & Dietary Supplement Formulation: Serves as a key active ingredient or a marker for standardization in supplements targeting anti-inflammatory and hepatoprotective benefits.
• Cosmetic & Skincare Actives: Incorporated into formulations for its potential skin-soothing, anti-irritant, and whitening properties.
• Biomedical Research: Utilized in in vitro and in vivo studies to investigate pharmacological activities, including anti-viral, anti-tumor, and metabolic regulation.
• Quality Control (QC) & Assurance: Essential for HPLC, LC-MS, and TLC methods to authenticate raw licorice material and ensure batch-to-batch consistency of final products.
• Traditional Medicine Modernization: Supports the scientific validation and standardization of licorice used in Traditional Chinese Medicine (TCM) and other herbal systems.

Basic Information

Product Name	24-Hydroxy-Licoricesaponin A3
CAS No.	1262326-47-5
Molecular Formula	C42H66O14
Molecular Weight	794.97 g/mol
Synonyms	24-Hydroxyglycyrrhizic acid; 24-Hydroxyglycyrrhizin; 24-Hydroxy-Licoricesaponin A3; 3β-[(2-O-β-D-Glucopyranuronosyl-α-D-glucopyranuronosyl)oxy]-11-oxoolean-12-en-24,30-dioic acid; 24-Hydroxy-Glycyrrhizic Acid; 24-Hydroxy-GL; 24-OH-GA; Licorice Saponin A3 derivative
EINECS	Contact for details

Quality Control

Our 24-Hydroxy-Licoricesaponin A3 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and MS for structural confirmation, and residual solvent analysis. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all test results against established specifications to ensure compliance with research and pharmaceutical-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, the container should be sealed under inert atmosphere or with desiccant after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥98.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.