Description

4'-Methoxy-2-Methyl-3'-(Trifluoromethyl)-[1,1'-Biphenyl]-4-Carboxylic Acid is a high-purity biphenyl carboxylic acid derivative, distinguished by its methoxy and trifluoromethyl substituents. This compound is a critical advanced pharmaceutical intermediate (API intermediate) valued for its role in constructing complex molecular scaffolds. It is primarily required by pharmaceutical R&D and manufacturing sectors for the synthesis of novel active ingredients, particularly in therapeutic areas demanding high structural specificity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially for small molecule drug candidates.
• Agrochemical Research: Used in the development of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Serves as a monomer or precursor for specialty polymers and liquid crystal materials, leveraging its rigid biphenyl core.
• Organic Synthesis & Catalysis: Employed as a sophisticated ligand or precursor in catalytic systems and complex multi-step organic transformations.
• Life Science Research: Utilized as a biochemical tool or probe in medicinal chemistry programs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	4'-Methoxy-2-Methyl-3'-(Trifluoromethyl)-[1,1'-Biphenyl]-4-Carboxylic Acid
CAS No.	1262006-62-1
Molecular Formula	C16H13F3O3
Molecular Weight	310.27 g/mol
Synonyms	4'-Methoxy-2-methyl-3'-(trifluoromethyl)biphenyl-4-carboxylic acid; [1,1'-Biphenyl]-4-carboxylic acid, 4'-methoxy-2-methyl-3'-(trifluoromethyl)-; 2-Methyl-4'-(methoxy)-3'-(trifluoromethyl)[1,1'-biphenyl]-4-carboxylic acid; 4-Carboxy-4'-methoxy-2-methyl-3'-trifluoromethylbiphenyl; Biphenyl-4-carboxylic acid derivative; TMF-Biphenyl acid; CAS 1262006-62-1
EINECS	Contact for details

Quality Control

Our production of 4'-Methoxy-2-Methyl-3'-(Trifluoromethyl)-[1,1'-Biphenyl]-4-Carboxylic Acid adheres to stringent quality protocols suitable for GMP-grade intermediates. Every batch is subjected to comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.