Description

5-Fluoro-2'-Hydroxy-[1,1'-Biphenyl]-3-Carboxylic Acid is a high-purity biphenyl derivative that serves as a critical advanced intermediate in modern organic synthesis. Its unique molecular structure, featuring both a carboxylic acid and a phenolic hydroxyl group on a fluorinated biphenyl scaffold, makes it a versatile building block for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical developers for the synthesis of novel active pharmaceutical ingredients (APIs) and functional materials, where precise chemical functionality is paramount.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Ligand and Catalyst Precursor: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Serves as a monomer or functional additive in the development of advanced polymers and liquid crystals with specific electronic or optical properties.
• Agrochemical Synthesis: Employed as a building block for creating novel herbicides and fungicides with enhanced efficacy and selectivity.
• Academic & Industrial R&D: Utilized in chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies.

Basic Information

Product Name	5-Fluoro-2'-Hydroxy-[1,1'-Biphenyl]-3-Carboxylic Acid
CAS No.	1261958-14-8
Molecular Formula	C₁₃H₉FO₃
Molecular Weight	232.21 g/mol
Synonyms	3'-Fluoro-6-hydroxybiphenyl-2-carboxylic acid; 5-Fluoro-2'-hydroxybiphenyl-3-carboxylic acid; [1,1'-Biphenyl]-3-carboxylic acid, 5-fluoro-2'-hydroxy-; 2'-Hydroxy-5-fluorobiphenyl-3-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 5-Fluoro-2'-Hydroxy-[1,1'-Biphenyl]-3-Carboxylic Acid is manufactured under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.