Description

3-(3,4-Methylenedioxyphenyl)-5-Trifluoromethylbenzoic Acid is a high-purity, functionalized benzoic acid derivative designed for advanced chemical synthesis. This compound is a critical building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, valued for its unique trifluoromethyl and methylenedioxyphenyl pharmacophores. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific structural motifs for enhanced bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for improved efficacy and environmental profile.
• Ligand & Catalyst Development: Used in organometallic chemistry and catalysis research to create novel ligands for transition metal complexes.
• Material Science Research: Employed in the synthesis of specialty polymers and organic electronic materials where its aromatic and fluorinated structure imparts specific properties.
• Chemical Biology Probe: Acts as a scaffold for developing molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	3-(3,4-Methylenedioxyphenyl)-5-Trifluoromethylbenzoic Acid
CAS No.	1261931-67-2
Molecular Formula	C15H9F3O4
Molecular Weight	310.23 g/mol
Synonyms	5-(Trifluoromethyl)-3-(1,3-benzodioxol-5-yl)benzoic Acid; 3-(Benzo[d][1,3]dioxol-5-yl)-5-(trifluoromethyl)benzoic Acid; 3-(3,4-Methylenedioxyphenyl)-5-(trifluoromethyl)benzoic Acid; 3-(1,3-Benzodioxol-5-yl)-5-(trifluoromethyl)benzoic Acid; 5-(Trifluoromethyl)-3-(3,4-methylenedioxyphenyl)benzoic Acid; 1261931-67-2; CAS 1261931-67-2
EINECS	Contact for details

Quality Control

Our production of 3-(3,4-Methylenedioxyphenyl)-5-Trifluoromethylbenzoic Acid adheres to stringent internal quality standards, ensuring batch-to-batch consistency and high purity suitable for research and scale-up. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We operate under a cGMP-compliant quality management system, and specifications can be aligned with customer-specific requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.