Description

1-(4-Chloro-3-(Trifluoromethyl)Phenyl)Propan-1-One is a high-purity fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its unique structure, featuring both chloro and trifluoromethyl substituents, makes it a critical intermediate for creating molecules with tailored electronic and steric properties. This compound is primarily sought by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules requiring fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated components in electronic display and lighting technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, carbonyl chemistry, and as a precursor for heterocyclic compounds in academic and industrial research.
• Polymer Modifier: Can be incorporated into specialty polymers to alter solubility, thermal stability, and chemical resistance.

Basic Information

Product Name	1-(4-Chloro-3-(Trifluoromethyl)Phenyl)Propan-1-One
CAS No.	1261861-70-4
Molecular Formula	C10H8ClF3O
Molecular Weight	236.62 g/mol
Synonyms	4'-Chloro-3'-(trifluoromethyl)propiophenone; 1-Propanone, 1-[4-chloro-3-(trifluoromethyl)phenyl]-; 4-Chloro-α-ethyl-3-(trifluoromethyl)benzenemethanol; 1-(4-Chloro-3-trifluoromethylphenyl)propan-1-one; Propiophenone, 4'-chloro-3'-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 1-(4-Chloro-3-(Trifluoromethyl)Phenyl)Propan-1-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, and NMR is supplied with each shipment to guarantee reproducible performance and supply chain reliability for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.