Description

Ethyl 2-Bromo-6-(Bromomethyl)Benzoate is a specialized brominated aromatic ester building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile precursor in the construction of complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and functionalized ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those with benzodiazepine or similar fused-ring structures.
• Agrochemical Research: Used in developing new generation herbicides and fungicides that require specific halogenated aromatic cores.
• Liquid Crystal & OLED Materials: Serves as a building block for creating bromo-functionalized aromatic units essential in electronic and photonic materials.
• Cross-Coupling Reactions: The bromine atoms provide excellent handles for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl systems.
• Polymer Modification: Employed to introduce aromatic and reactive bromomethyl groups into polymer backbones for specialty polymers.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or affinity probes due to its reactive benzylic bromide functionality.

Basic Information

Product Name	Ethyl 2-Bromo-6-(Bromomethyl)Benzoate
CAS No.	1261851-80-2
Molecular Formula	C10H10Br2O2
Molecular Weight	322.00 g/mol
Synonyms	Ethyl 2,6-Dibromomethylbenzoate; 2-Bromo-6-(bromomethyl)benzoic Acid Ethyl Ester; Benzoic acid, 2-bromo-6-(bromomethyl)-, ethyl ester; Ethyl 2-Bromo-6-(bromomethyl)benzoate; 1261851-80-2; Ethyl α,2-Dibromo-o-toluate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Bromo-6-(Bromomethyl)Benzoate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature and reactive bromomethyl group, prolonged exposure to light, heat, or moisture should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.