Description

6-Iodo-o-Tolualdehyde (2-Formyl-3-Iodotoluene) is a versatile halogenated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an aldehyde group and an iodine atom on a toluene backbone, makes it a critical intermediate for constructing complex molecules through cross-coupling and functional group transformation reactions. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The iodine atom acts as an excellent handle for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings to form biaryl and other complex structures.
• Organic Synthesis & Research: A valuable reagent for academic and industrial research laboratories exploring new synthetic methodologies and heterocyclic chemistry.
• Ligand and Catalyst Development: Used to synthesize novel chelating ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	6-Iodo-o-Tolualdehyde / 2-Formyl-3-Iodotoluene
CAS No.	1261826-51-0
Molecular Formula	C8H7IO
Molecular Weight	246.05 g/mol
Synonyms	2-Formyl-3-iodotoluene; 3-Iodo-2-methylbenzaldehyde; 6-Iodo-2-methylbenzaldehyde; o-Tolualdehyde, 6-iodo-; 2-Methyl-3-iodobenzaldehyde; 2-Methyl-6-iodobenzaldehyde; 3-Iodo-o-tolualdehyde
EINECS	Contact for details

Quality Control

Every batch of 6-Iodo-o-Tolualdehyde is produced and tested under a strict quality management system to ensure consistency and reliability for your critical synthesis work. We provide comprehensive analytical data including HPLC purity, NMR, and GC-MS to verify identity and quality. A Certificate of Analysis (COA) is supplied with each shipment, and we support custom purity requirements for specific research or production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.