Description

1-(4-Bromo-2-Iodo-Phenyl)-Ethanone is a high-purity halogenated aromatic ketone building block, essential for advanced organic synthesis. Its distinct bromo and iodo substituents on the phenyl ring make it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a building block for creating advanced organic materials, such as liquid crystals, organic semiconductors, and photoactive polymers.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Heck) due to the presence of both bromo and iodo leaving groups, allowing for sequential functionalization.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-(4-Bromo-2-Iodo-Phenyl)-Ethanone
CAS No.	1261792-99-7
Molecular Formula	C8H6BrIO
Molecular Weight	324.94 g/mol
Synonyms	4'-Bromo-2'-iodoacetophenone; 1-Acetyl-4-bromo-2-iodobenzene; 4-Bromo-2-iodoacetophenone; 2-Iodo-4-bromoacetophenone; Ethanone, 1-(4-bromo-2-iodophenyl)-; (4-Bromo-2-iodophenyl)ethanone; 4-Bromo-2-iodophenylethanone; 1-(4-Bromo-2-iodophenyl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 1-(4-Bromo-2-Iodo-Phenyl)-Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.