Description

2-Bromo-1-(5-Bromo-2-Chlorophenyl)Ethanone is a high-purity, multi-halogenated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring bromine and chlorine substituents at strategic positions, makes it a versatile and reactive intermediate for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is primarily utilized by research institutions and industrial R&D departments focused on developing new active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Serves as a building block for developing new herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of organic electronic materials, liquid crystals, and advanced polymers where halogenated aromatic units are required.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of chemical probes for target identification and validation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules on scale.

Basic Information

Product Name	2-Bromo-1-(5-Bromo-2-Chlorophenyl)Ethanone
CAS No.	1261775-99-8
Molecular Formula	C8H5Br2ClO
Molecular Weight	312.39 g/mol
Synonyms	2-Bromo-1-(5-bromo-2-chlorophenyl)ethan-1-one; 5'-Bromo-2'-chlorophenacyl Bromide; α-Bromo-5-bromo-2-chloroacetophenone; 1-(5-Bromo-2-chlorophenyl)-2-bromoethanone; 2-Bromo-5-bromo-2-chloroacetophenone; (5-Bromo-2-chlorophenyl)bromomethyl ketone; NSC 403796
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1-(5-Bromo-2-Chlorophenyl)Ethanone is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with each shipment. Our quality protocols are designed to support cGMP (current Good Manufacturing Practice) compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.